Securing Enterprise Agents with NVIDIA OpenShell and Cisco AI Defense

NVIDIA OpenShell and Cisco AI Defense are presented as a combined security framework for enterprise autonomous agents. OpenShell provides sandbox containment, deny-by-default access, per-endpoint network policy, and privacy routing at the infrastructure level. Cisco AI Defense adds supply chain verification for AI tools and skills, continuous MCP tool call inspection, and audit-grade tracing of agent behavior. A fictional zero-day response scenario illustrates how the two layers work together: agents reason over a live knowledge graph to identify vulnerable devices, plan remediation, and file tickets—while OpenShell constrains what they can do and AI Defense blocks a detected prompt injection/exfiltration attempt in an MCP call before any sensitive data leaves the environment.