A Rust developer working with bioinformatics data discovered a significant performance optimization when using LZ4 compression. By swapping the order of BufWriter and LZ4 Encoder in the chain (buffering writes to the encoder instead of to the file), they achieved a 1.83x speed improvement. The issue was that small MessagePack chunks (~250 bytes) were causing excessive LZ4 block operations, and buffering at the encoder level reduced these costly operations.

4m read timeFrom deterministic.space
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Compression with LZ4ProfilingSwap the buffer

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