NVIDIA's RTX PRO 4500 Blackwell Server Edition GPU delivers significant performance gains for genomics and protein folding workloads. Benchmarks show 2x speedups over the L4 GPU for Minimap2 and DeepVariant, 2.4x for fq2bam alignment, and up to 2.3x faster protein structure inference with OpenFold3 and cuEquivariance. For Smith-Waterman alignment, the RTX PRO 4500 achieves 19.2x over CPU baseline and performs on par with H100 SXM at 4.3x lower power. PacBio reports over 2x basecalling throughput improvement. Docker-based quickstart commands are provided for Minimap2, fq2bam, and DeepVariant via NVIDIA Parabricks v4.7.
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NVIDIA Parabricks on NVIDIA RTX PRO 4500 BlackwellAccelerating alignment and variant calling: Minimap2, fq2bam, and DeepVariantParabricks v4.7 benchmarksGet started with Minimap2Get started with fq2bam (BWA-MEM)Get started with DeepVariantAdvancing structural biology with Openfold3 and cuEquivarianceHigh performance in Smith-Waterman alignmentLearn moreSort: