The python-telegram-bot v20 release introduced major structural changes. According to the documentation, > “All networking and I/O-related logic now works via coroutine functions (i.e.  async def ... functions). In particular, all methods of the telegram.Bot class that make requests to the Bot API are now coroutine functions and need

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Learn how to migrate from python-telegram-bot v13 to v20, use webhooks instead of polling, and deploy a python-telegram-bot v20 webhook with Flask and FastAPI.

How to Build and Deploy a python-telegram-bot v20 Webhook

The Challenge of using Flask with python-telegram-bot v20

How to Do It — Migration and Deployment